Dosing & Administration

How to administer Adequan® Canine to proactively treat canine osteoarthritis (OA) disease, not just the clinical signs.1

Veterinarians can prescribe Adequan Canine (polysulfated glycosaminoglycan) at the first signs of OA or degenerative joint disease (DJD) to manage clinical signs and help slow the disease process. The results shown in clinical studies were achieved by following the approved dosing regimen.1,2 After the initial series, the veterinarian and pet parents should work together to monitor the dog’s joint health and mobility. The dosing regimen may be repeated as needed upon recurrence of clinical signs.

Adequan Canine Veterinarian dog clinic
Adequan Canine Start With It
  • Use Adequan® Canine early, at the first clinical signs of OA before it progresses, and cartilage is irreversibly damaged.1
  • Administer twice a week (3-to-5-day intervals) for up to 4 weeks (maximum of 8 injections) at approved dosage of 4.4 mg/kg (2 mg/lb) body weight (0.02 mL/lb or 1 mL/50 lb) by intramuscular (IM) injection only.1 Do not exceed the recommended dose or therapeutic regimen. Do not mix Adequan® Canine with other drugs or solvents. Avoid inadvertent intravascular administration.
  • You may see signs of improvement within one month.2
Adequan Canine Stay With It
  • Continue to prescribe Adequan® Canine as needed to help slow down the clock of arthritis.

How Adequan® Canine (polysulfated glycosaminoglycan) can help extend a dog’s mobility over a lifetime.

Adequan Canine lifetime of mobility chart

IM injection provides fast relief and reliable delivery to synovial joints.

Within 2 hours, Adequan® Canine reaches synovial joints to begin helping to restore joint tissues that are damaged or inflamed — and lasts for approximately 3 days.1
Adequan® Canine Polysulfated Glycosaminoglycan (PSGAG) Sterile Injection 100 mg/mL
INDICATIONS Adequan® Canine is recommended for the treatment of non-infectious degenerative and/or traumatic arthritis and associated lameness of canine synovial joints.
IMPORTANT SAFETY INFORMATION Adequan® Canine is for veterinary use only. The prescribing information contains complete use information which includes dosing, contraindications, warnings and cautions. Always read, understand and follow label and use directions. PLEASE CONSULT the Full Prescribing Information.
1. Adequan® Canine (polysulfated glycosaminoglycan sterile injection 100 mg/mL), Package Insert IN00502C. American Regent, Inc.
2. Data on File.
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