How Adequan® Canine Works

Restore. Relieve. Renew.

As the only approved PSGAG disease-modifying osteoarthritis drug (DMOAD), Adequan® Canine (polysulfated glycosaminoglycan) has a mode of action that empowers you to actively treat the disease, not just the clinical signs.1


Here’s how it may help:

Binds to components of the cartilage matrix to help prevent further degradation of the joints.

  • Reduces inflammation and decreases pain.
  • Inhibits release of degradative enzymes and inflammatory mediators to help restore balance.
  • Stimulates the activity of existing cartilage components and improves synovial fluid to help renew joint mobility.

Discover if Adequan® Canine is the right choice.

Adequan Canine how it works joint

Adequan Canine how it works joint

The Foundation of Multimodal OA Therapy

Adopting a multi-modal approach2 that focuses on helping your dog get better, and feel better, may slow the progression of osteoarthritis (OA) from early to late stages.

Adequan Canine multimodal oa therapy

Discover if Adequan® Canine is the right choice.

Help slow down the OA clock with a comprehensive plan.

Develop a personalized multi-modal plan that is specific to each patient that can include disease treatment, pain management, exercise, weight control and physical therapy.

Osteoarthritis (OA)
Need To Treat Early
Video Transcript

Mark E. Epstein
DVM, DABVP (C/F), CVPP

“...we only have a certain amount of capital of time and attention from the owner. So it does make it a significant challenge.

“My guidance would be that with any inclination of a COAST (Canine Osteoarthritis Staging Tool) one or a two dog, that if you can make sure that the subject is brought forward, it is introduced to the client at that point, then you will have gone a step further than probably you otherwise would have. If we can move the profession that far, that’s an important step to take.”

Denis J. Marcellin-Little
DEDV, DACVS, DECVS, DACVSMR

“It is in the patients, the owners, and our best interests to manage osteoarthritis from its early stages, not from its late stages.”

Julia Tomlinson
BVSc, MS, PhD, DACVS, CCRP, CVSMT, DACVSMR

“If we start treating very late in the disease, then we’re really just trying to play catch up. We’ve already lost some motion in the joint so you have some stiffness that’s going to factor in and feed into pain and inactivity, which again is going to feed into other problems in practice such as obesity.”

The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.

NP-NA-US-0344

"The optimal management of OA focuses on strategies
that slow down the clock."

Denis J. Marcellin-Little,
DEDV, DACVS, DECVS, DACVSMR

Adequan® Canine Polysulfated Glycosaminoglycan Sterile Injection 100 mg/mL
INDICATIONS Adequan® Canine is recommended for the treatment of non-infectious degenerative and/or traumatic arthritis and associated lameness of canine synovial joints.
IMPORTANT SAFETY INFORMATION Adequan® Canine is for veterinary use only. The prescribing information contains complete use information which includes dosing, contraindications, warnings and cautions. Always read, understand and follow label and use directions. PLEASE CONSULT the Full Prescribing Information.
1. Adequan® Canine (polysulfated glycosaminoglycan sterile injection 100 mg/mL), Package Insert IN00502C. American Regent, Inc.
2. 2015 AAHA-AAFP Pain Mgt. Guidelines for Dogs and Cats; J Am Anim Hosp Assoc 2015; 51_67-87. DOI 10.5326JAAHA-MS-7331.
AMERICAN REGENT ANIMAL HEALTH
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